経口避妊薬使用中に抗生物質を使うときの注意　

1999/6/23　ロイター　英国の調査では、救急外来に働く医師たちは、抗生物質投与がピルの避妊が失敗して妊娠が起こりやすくなることをしばしば告げていないという。抗生物質投与中と中止後７日間はコンドームを使用することをすすめるべきと。

MDs often forget antibiotic warning for Pill users

NEW YORK, Jun 23 (Reuters Health) -- British researchers report that doctors working in UK emergency rooms often fail to inform women taking oral contraceptives that antibiotics can cause the Pill to fail, increasing their risk of pregnancy.
In a small survey of 12 UK doctors, only 5 were correct when asked what advice should be given to women on the Pill to whom they were about to give antibiotics, according to Michelle H. Mullan and Adrian R. Harris of Exeter Hospital in Exeter, England. ``One gave incorrect advice, five gave inadequate advice, and one gave no advice at all,'' they write.
Their review of prescription records confirmed the lack of attention to contraceptive medication. Among 21 women prescribed antibiotics, ``only two (9.5%) had received documented contraceptive advice,'' according to their report in the July issue of the Journal of Accidental and Emergency Medicine.
A second report published in the same issue examined doctors' notes for 100 female emergency patients of childbearing age who were prescribed antibiotics.
Dr. Alison Gammon and co-workers from Mandeville Hospital in Aylesbury, England, note that a previous study showed that 39% of UK women between the ages of 15 and 39 were on the Pill. But their study found only three charts had written evidence that the patient was asked about her method of contraception.
According to both reports, women on the Pill should take additional contraceptive precautions (using condoms, for example) while taking antibiotics and for an additional 7 days after finishing the course of antibiotics.
SOURCE: Journal of Accidental and Emergency Medicine 1999;16:265-267, 268-270.