低量のアスピリンは体外受精胚移植の成功率を向上させる　

1999/4/26　ロイター　アルゼンチンの研究によると、体外受精のための卵巣刺激中に低量のアスピリンを用いると妊娠率が向上するという。子宮卵巣への血流が増加するため卵巣の反応性が増加し、着床率もよくなるらしい。

Aspirin helps infertility treatment

NEW YORK, Apr 26 (Reuters Health) -- Women undergoing in vitro fertilization (IVF) are more likely to become pregnant if they take low doses of aspirin in conjunction with drugs that stimulate ovulation, a study suggests.
Dr. Ester Polak de Fried and colleagues, of CER Medical Institute in Buenos Aires, Argentina, compared 149 women who took a daily dose of 100 milligrams of aspirin while taking ovulation-stimulating drugs to 149 ``control'' women undergoing the same IVF treatment who did not take aspirin.
They found that 45% of women in the aspirin group became pregnant compared with 28% in the control group. On average, 19.8 follicles and 16.2 oocytes (eggs) were retrieved from the aspirin-treated women compared with 10.2 and 8.6, respectively, from the women who did not receive aspirin.
``Low-dose aspirin treatment significantly improves ovarian response, uterine and ovarian blood flow velocity, implantation rate, and pregnancy rate in patients undergoing IVF,'' the investigators report in the May issue of Fertility and Sterility. ``Aspirin seems to be a useful, effective, and safe treatment in patients who undergo assisted reproductive technologies,'' Polak de Fried and colleagues conclude.
SOURCE: Fertility and Sterility 1999;71:825-829.